Dr. Virendra Chauhan

+91 9503815011

drvirendra91@yahoo.com

Dr. Virendra Chauhan

MBBS, DNB Medicine, DrNB Nephrology

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ABO Incompatible Transplants

ABO Incompatible Transplants

ABO incompatible transplants refer to organ transplants where the donor and recipient have different blood types. Typically, organ transplants require compatibility between the blood types of the donor and recipient to reduce the risk of rejection. However, ABO incompatible transplants allow for transplantation even when the donor and recipient blood types do not match. Here are key points about ABO incompatible transplants:

Reasons for ABO Incompatibility

Limited Donor Pool: ABO incompatibility can expand the pool of potential donors, especially in situations where compatible donors are scarce.

Emergency Situations: In urgent cases where waiting for a compatible donor may not be feasible due to the recipient's critical condition, ABO incompatible transplants offer a viable option..

Alternative for Sensitized Patients: Patients who have developed antibodies against potential donors (due to previous transplants, blood transfusions, or pregnancies) may benefit from ABO incompatible transplants.

Procedure

Immunosuppression: Recipients receive immunosuppressive medications to suppress their immune system's response and reduce the likelihood of rejection.

Monitoring: Regular monitoring of antibody levels and kidney function post-transplant is essential to detect and manage rejection early.

ABO incompatible transplants represent an important option for expanding the donor pool and providing life-saving treatments to patients who might not otherwise have a compatible donor. While they involve additional challenges and risks, advances in medical techniques and careful patient management have made these transplants increasingly feasible and successful.

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